Determination of proliferative activity in nasal polyps.

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Determination of proliferative activity in nasal polyps.

AIMS To determine the level of proliferative activity in 39 nasal polyps with clear cut distinct clinical behaviour patterns. METHODS The 39 nasal polyps included 11 polyps labelled as "single" and taken from the lateral nasal wall and the middle turbinate; 12 polyps labelled as "massive" and relating to diffuse polyposis involving the entire nasal cavity; six polyps labelled as "ASA" and rel...

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The proliferative activity and growth pattern of 20 seminomas were determined immunohistologically with the monoclonal antibody Ki-67. A growth fraction of tumour cells between 50 and 80% was found in seminomas with an almost even distribution of proliferating cells in all sections, regardless of tumour size. There was a slight tendency towards a greater growth fraction in tumours at an advance...

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Epidemiology of Nasal Polyps

Mounting evidence suggests that nasal polyposis (NP) is a clinical manifestation of multiple possibly coexisting immunologic pathways, and because this entity likely reflects an array of disease states, the epidemiology is difficult to characterize. Phenotypically, chronic rhinosinusitis (CRS) can be classified as either CRS without NP or CRS with NP. CRS without NP, in general, reflects TH1-me...

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[Cathepsin D activity in chronic rhinosinusitis with nasal polyps].

UNLABELLED Nasal polyposis affects about 1 to 4% of the population. Polyps develop in oedematous and inflammated mucous membrane. In spite of the intensive research the pathomechanism of their development is not fully understood. The majority of the theories concerning the development of nasal polyps emphasize the role of the inflammatory process causing the rupture of the epithelium and the ba...

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Lysosomal exoglycosidases in nasal polyps.

INTRODUCTION Nasal polyps are smooth outgrowths assuming a shape of grapes, formed from the nasal mucosa, limiting air flow by projecting into a lumen of a nasal cavity. Up to now the surgical resection is the best method of their treatment, but etiology and pathogenesis of the nasal polyps is not yet fully established. AIM OF THE STUDY The aim of the study was the assessment of the selected ...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1997

ISSN: 0021-9746

DOI: 10.1136/jcp.50.11.923